Asymptomatic Transmission & Shedding

Comparison of Virus Shedding After Rotavirus Vaccines

Captured 2023-03-10
Document Highlights

Transmission of rotavirus vaccine or vaccine-reassortant strains to unvaccinated contacts has been reported.

Two groups of healthy infants who received a complete course of RotaTeq or Rotarix were enrolled to compare fecal shedding for one month after each vaccine dose.

After the first vaccine dose, the peak time of virus shedding occurred between day 4 and day 7

In both groups, vaccine shedding occurred as early as one day and as late as 25-28 days.