Although propylene glycol is regarded as having low toxicity in adults, in humans and animals there have been reports of CNS, renal, hematologic, and cardiac toxicity.
[S]everal infants in our nursery were hyperosmolar due to administration of propylene glycol in a multivitamin preparation used in parenteral nutrition.
"HHS [hyperglycemic hyperosmolar syndrome] is a condition of:
Extremely high blood sugar (glucose) level
Extreme lack of water (dehydration)
Decreased alertness or consciousness (in many cases)"
Source: Medline Plus
Parenteral = intravenous, intramuscular, subcutaneous, or intradermal administration.
Preservative Free Vitamin K Injection contains propylene glycol.
