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NCVIA / VICP / VAERS
National Childhood Vaccine Injury Act
National Childhood Vaccine Injury Act of 1986
Bruesewitz V Wyeth 2010 NCVIA
Bruesewitz V Wyeth Impact on vaccine safety debate
Vaccine Injury Compensation Program
VICP Fact Sheet
VICP May 2019 Payout
Vaccine injury compensation and legal representation for GBS
Vaccine Adverse Events Reporting System
About the Vaccine Adverse Events Reporting System
AHRQ report on VAERS
Vaccine Inserts
All Inserts
List of All Current US Vaccine Inserts
Diphtheria / Tetanus / Pertussis
Pedarix [DTaP/Hep B/IPV]
Pentacel [DTaP/Hib/IPV]
Haemophilus influenzae type b
PedvaxHIB
Pentacel [DTaP/Hib/IPV]
Hepatitis B
Engerix-B
Pedarix [DTaP/Hep B/IPV]
Human papillomavirus HPV
Gardasil 9 HPV
Influenza
Fluvirin
FluMist Quadrivalent
Measles / Mumps / Rubella
MMR II
Pneumococcal
Prevnar 13
Polio
Pedarix [DTaP/Hep B/IPV]
Pentacel [DTaP/Hib/IPV]
Vitamin K
AquaMEPHYTON
Vitamin K1 Hospira
Preservative Free Phytonadione Injectable
Vaccine Ingredients / Excipients / Contaminants
Overview
CDC vaccine excipient and media summary
Vaccine ingredient glossary and details
Aluminum Adjuvants
Aluminum involvement in neurotoxicity
Contact allergy to aluminium induced by commonly used pediatric vaccines
Aluminum hydroxide injections lead to motor deficits and motor neuron degeneration
Administration of aluminum to neonatal mice in vaccine relevant amounts is associated with long term neurological outcomes
Biopersistence and brain translocation of aluminum adjuvants of vaccines
Aluminum in childhood vaccines is unsafe
Aborted Fetal Cell DNA
MRC 5 human lung fibroblast
WI 38 human lung fibroblast
Spontaneous integration of human dna fragments into host genome
Characteristics of a new human diploid cell line walvax 2 and its suitability as a candidate for vaccine production
Thimerosal / Mercury
Effect of thimerosal, methylmercury, and mercuric chloride in Jurkat T Cell Line
Low dose mercury exposure in early life relevance of thimerosal to fetuses newborns and infants
Thimerosal induces dna breaks and cell death in cultured human neurons
Review of neurotoxicity studies of low-dose thimerosal relevant to vaccines
Polysorbate 80
The blood brain barrier bottleneck in brain drug development
Specific role of polysorbate 80 coating on the targeting of nanoparticles to the brain
Fetal Bovine Serum
The use of fetal bovine serum
Propylene Glycol
Hyperosmolality in small infants due to propylene glycol
Glyphosate
Glyphosate pathways to modern diseases VI Prions amyloidoses and autoimmune neurological diseases
Asymptomatic Transmission & Shedding
Pertussis Whooping Cough
FDA study helps provide an understanding of rising rates of whooping cough
Acellular pertussis vaccines protect against disease but fail to prevent infection and transmission
Acellular pertussis vaccination facilitates bordetella parapertussis infection
The impact of parental postpartum pertussis vaccination on infection in infants
Finding the who in whooping cough
Live virus vaccines
Horizontal transmission of live vaccines
Measles
Post vaccine measles in a child in Italy
Vaccine associated measles five weeks post immunisation
Chicken Pox
Transmission of varicella vaccine virus from child to pregnant mother
Shingles
Varicella zoster virus DNA at inoculation sites and in saliva after zostavax immunization
Rotavirus
Comparison of virus shedding after rotavirus vaccine
Influenza
Infectious virus in exhaled breath of symptomatic seasonal influenza cases
Hepatitis A
Development production and postmarketing surveillance of hepatitis A vaccines in China
Mumps
Horizontal transmission of mumps vaccine virus
Transmission of mumps vaccine virus in Croatia
Polio
Inactivated polio vaccine shedding
Vaccine-derived polio
Effectiveness / Outbreaks / Herd Immunity
Effectiveness
What are the limits of adjuvanticity?
Antibodies are not required for immunity against some viruses
B cell maintenance protects against fatal viral infection independent of adaptive immunity
Severe tetanus in immunized patients with high anti tetanus titers
Waning Protection
Measles outbreak traced to fully vaccinated patient
Vaccine development needs a booster shot
Waning protection after fifth dose of acellular pertussis vaccine
FluMist
ACIP votes down use of LAIV for 2016-2017 flu season
Potential Consequences of Not Using Live Attenuated Influenza Vaccine
CDC vaccine panel brings back FluMist for 2018-19 season
Update ACIP Recommendations for the use of quadrivalent live attenuated influenza vaccine 2018-19 season
Live Attenuated Influenza Vaccine LAIV
Outbreaks in Vaccinated Populations
LA Countywide Outbreak Of Whooping Cough
Chickenpox outbreak in a highly vaccinated school population
Influenza outbreak in a vaccinated population USS Ardent 2014
Major measles epidemic in the region of Quebec despite a 99 percent vaccine coverage
Measles outbreak in a fully immunized secondary school population
Whooping cough outbreak on long island
Fordham university mumps outbreak jumps campuses
Influenza potentially made stronger by vaccines
Herd Immunity
Herd immunity and compulsory vaccination does the theory justify the law
Necessity Of Vaccination
Before the Vaccines
Vital statistics measles reports from general practitioners
Decline in Disease Mortality
The questionable contribution of medical measures to the decline of mortality in the United States in the twentieth century
CDC history of drinking water treatment
CDC vital statistics death rates for measles and diphtheria
CDC vital statistics death rates for tuberculosis and typhoid fever
Effective Treatments
In vitro inhibition of mumps virus by retinoids
Ascorbic acid vitamin C treatment of whooping cough
Rotavirus neutralisation by human milk
Human milk mucin inhibits rotavirus replication and prevents experimental gastroenteritis
Vitamin B6 prevents cognitive impairment in experimental pneumococcal meningitis
Vitamin C for preventing and treating pneumonia
Measles
A randomized controlled trial of vitamin A in children with severe measles
Routine high dose vitamin A therapy for children hospitalized with measles
Low serum retinol is associated with increased severity of measles
Measles severity and serum retinol vitamin A concentration among children in the United States
Persistent measles infection in malnourished children
Vitamin A for the treatment of children with measles A systematic review
Vitamin A supplements for preventing mortality and illness in children under five A systematic review and meta analysis
Vitamin A supplements for children could save six hundred thousand lives a year
Retinoids inhibit measles virus in vitro via nuclear retinoid receptor signaling pathways
Retinoids inhibit measles virus through a type one IFN dependent bystander effect
The Case of Polio
Epidemiology and prevention of poliomyelitis
Adverse Reactions
Autism
A positive association found between autism prevalence and childhoood vaccination uptake across the US population
Do aluminum adjuvants contribute to the rising prevalence of autism
A possible central mechanism in autism spectrum disorders
Hepatitis B vaccination of male neonates and autism diagnoses
Aluminum in brain tissue in autism
Impact of environmental factors on the prevalence of autistic disorder after 1979
Epidemiologic and molecular relationship between vaccine manufacture and autism spectrum disorder prevalence
Newborn immune activation may have long term negative impact on brain function
Family to receive first ever vaccine autism court award
High rates of autism found in federal vaccine injury program
What is regressive autism and why does it occur?
Autoimmunity
Congitive dysfunction associated with aluminum hydroxide induced macrophagic myofaciitis
Descriptive analysis of 300 patients from the international ASIA syndrome registry
Adjuvants and vaccines induced autoimmunity animal models
HPV vaccination syndrome a questionnaire based study
Chronic fatigue syndrome and fibromyalgia following immunization with the Hepatitis B vaccine
Evolution of multiple sclerosis in France since hepatitis B vaccination
POTS with chronic fatigue after HPV vaccination as part of ASIA
ASIA 2013 unveiling the pathogenic clinical and diagnostic aspects
Autoimmune autoinflammatory syndrome induced by adjuvants animal models as proof of concept
Macrophagic myofaciitis characterization and pathophysiology
The common immunogenic etiology of chronic fatigue syndrome from infections to vaccines via adjuvants to the asia syndrome
Macrophagic myofaciitis a vaccine alum autoimmune related disease
Editorial on ASIA highlighting different perspectives for diffuse chronic pain
Chronic fatigue syndrome in patients with macrophagic myofasciitis
Identical twins with macrophagic myofaciitis
Aluminum phagocytosis in quadriceps muscle following vaccination in children
The development of rheumatoid arthritis after recombinant hepatitis B vaccination
Demyelination
Transverse myelitis and vaccines a multi analysis
The spectrum of post vaccination inflammatory cns demyelinating syndromes
Hepatitis B vaccine and the risk of cns inflammatory demyelination in childhood
Evolution of multiple sclerosis in France since hepatitis B vaccination
Febrile Seizures
Measles Mumps Rubella Varicella vaccine and the risk of febrile seizures
Fertility
HPV vaccine and primary ovarian failure
A lowered probability of pregnancy in females who received HPV vaccine
Association of spontaneous abortion with receipt of inactivated influenza vaccine
Genetic Susceptibilities
Genetic basis for adverse events following smallpox vaccination
TellMeGen genetic testing Hypersensitivity to vaccination
Hospitalization
Adverse events following 12 and 18 month vaccinations
Children who get flu vaccine have three times risk of hospitalization for flu
Infections
Increased risk of noninfluenza respiratory virus infection with receipt of vaccine
Live Attenuated Influenza Vaccine Enhances Colonization of Streptococcus pneumoniae and Staphylococcus aureus in Mice
Live Attenuated Influenza Virus Increases Pneumococcal Translocation and Persistence Within the Middle Ear
Effect of pneumococcal conjugate vaccine on nasopharyngeal bacterial colonization during acute otitis media
Meningitis
Haemophilus influenzae type b meningitis in the short period after vaccination
Neuropsychiatric Disorder
Vaccines linked to mental disorders by Yale study
Temporal association of neuropsychiatric disorders following vaccination of children and adolescents
Nonfebrile Seizures
Nonfebrile seizures after MMRV virus combination vaccination
Optic Neuritis
Optic neuritis following DTaP and inactivated polio combined vaccine
Optic neuritis in pregnancy after Tdap vaccination
Rapid onset optic neuritis following measles vaccine in India
Adverse neurologic reactions after both doses of pandemic H1N1 influenza vaccine with optic neuritis and demyelination
The role of infection and vaccination in the genesis of optic neuritis and multiple sclerosis in children
SIDS / Death
Infant mortality rates regressed against number of vaccine doses given
Simultaneous sudden infant death syndrome
VICP sids court ruling
Incentives / Marketing / Misconduct
Centers for Disease Control and Prevention
SPIDER Bites CDC
The CDC is being influenced by corporate and political interests
Cochrane Review
The Cochrane HPV vaccine review was incomplete and ignored important evidence of bias
Department of Health and Human Services
ICAN HHS Lawsuit
Incentives
Pay for Performance Provider Incentive Programs
IEHP Pay for Performance program immunizations
2018 P4P Guide for independent physician associations
2015 California Medicaid Provider Incentive Program
2016 BCBS Michigan provider incentive program
2017 BCBS Michigan performance recognition program
2017 Indiana Medicaid pay for performance
Marketing
Increasing uptake of influenza vaccination
Global Vaccine Market Features and Trends
Medical Education
Conflict of Interest in Medical Research Education and Practice
Scientific Research
How many scientists fabricate and falsify research
Vaccine Manufacturers
Merck has some explaining to do over its MMR vaccine claims
GlaxoSmithKline Agrees to Pay $3 Billion in Fraud Settlement
Polio
The present status of polio vaccines
The Truth About the Polio Vaccines
Retinoids inhibit measles virus in vitro via nuclear retinoid receptor signaling pathways
