A trio of recent publications in the journal NEURON reports the presence of hundreds of diverse de novo gene mutations indicating that autism spectrum disorder (ASD) may be a disease of genomic instability, with a significant environmental component.
We hypothesize that the HERVK and human fetal DNA contaminants could contribute to the genomic instability of ASD as demonstrated by de novo mutations.
Vaccines manufactured using human fetal cells contain residual DNA fragments (50-500 bp).
Increased DNA uptake after LPS activation suggests that systemic inflammation or immune responses could increase susceptibility for exogenous DNA uptake.
Human diploid cell produced vaccines are contaminated by exogenous DNA fragments and a retrovirus, and vaccines elicit systemic inflammation and immune activation.
Not only damaged human cells, but also healthy human cells can take up foreign DNA spontaneously.
Foreign human DNA taken up by human cells will be transported into nuclei and be integrated into host genome, which will cause phenotype change.