"Research indicates that patients with impaired kidney function, including premature neonates, who receive parenteral levels of aluminum at greater than 4 to 5 mcg/kg/day accumulate aluminum at levels associated with central nervous system and bone toxicity. Tissue loading may occur at even lower rates of administration."
Source: Vitamin K1 Injection (Phytonadione) insert, Code of Federal Regulations Title 21
There is no existing safe limit of injection for infants who have healthy kidney function. The above acknowledgment - that injecting 4 to 5 micrograms of aluminum per kilogram of body weight, per day, can cause tissue loading in patients with impaired kidney function - is the only observation regarding the toxicity of injecting aluminum that has been recorded in research.
Neither a NOAEL or Reference Dose has been determined for injecting aluminum into the human body.
"Healthy babies may be able to handle quantities of aluminum above FDA toxicity levels indicated for patients with impaired kidney function. However, no one knows how much more aluminum is safe because adequate studies were never conducted. In addition, babies are not screened for renal function prior to vaccination. Therefore, it is impossible to know ahead of time which babies will succumb to aluminum poisoning."
Source: Aluminum in Childhood Vaccines is Unsafe
Using a 5mcg/kg/day as a "safe limit" of injection, what is the safe limit for the average newborn?
A newborn typically weighs approximately 7.5lbs, or 3.5kg.
Multiply safe limit by weight of newborn for safe limit per day for a newborn of average weight:
(5mcg/kg/day)(3.5kg) = 17.5 micrograms/day.
The hepatitis B vaccine, Engerix-B, contains 250 mcg aluminum, over 14x this "safe limit".
Aluminum content of licensed vaccines:
Note that multiple aluminum-containing vaccines may be given at a single doctor's visit. CDC Schedule
330 mcg - Daptacel (DTaP)
625 mcg - Infanrix (DTaP)
600 mcg - Kinrix (DTaP/Polio)
850 mcg - Pediarix (DTaP /Polio/Hep B)
330 mcg - Pentacel (DTaP/Polio/HIB)
330 mcg - Quadracel (DTaP / Polio)
319 mcg - Vaxelis (DTaP/Polio/Hep B/HIB)
225 mcg - PedvaxHIB (H. influenzae B)
250 mcg - Havrix (Hepatitis A)
225 mcg - Vaqta (Hepatitis A)
450 mcg - Twinrix (Hepatitis A & B)
250 mcg - Engerix-B (Hepatitis B)
500 mcg - Recombivax (Hepatitis B)
500 mcg - Gardasil 9 (HPV)
519 mcg - Bexsero (Meningococcal B)
125 mcg - Prevnar (Pneumococcal)
125 mcg - Vaxneuvance (Pneumococcal)
330 mcg - Tenivac (Tetanus & Diptheria)
330 mcg - Adacel (Tdap)
390 mcg - Boostrix (Tdap)
The greatest amount of aluminum contained in any single shot is 850 mcg (Pediarix). This vaccine is typically given alongside two other aluminum containing vaccines (pneumococcal - 125 mcg and HIB - zero to 225 mcg) at 2 months, 4 months, and 6 months of age. (See CDC Schedule.)
The average 2 month old weighs approximately 11.8 lbs, or 5.35kg.
(5 mcg/kg/day) (5.35kg) = 26.75 mcg/day "safe limit" for average 2 month old.
Aluminum (Al) injected at 2 month doctor's visit: 850 mcg (Pediarix) + 125 mcg (Prevnar 13 or Vaxneuvance) + 225 mcg (Pedvax HIB) = 1,200 mcg
Comparing aluminum exposure from breastmilk vs vaccines:
"A single dose of [a] vaccine [containing 820 mcg alum] is equivalent to the exposure to aluminium that an infant would receive from 150 days breast-feeding."
"[I]t is not uncommon for an infant to receive... three... aluminium adjuvanted vaccines on the same day."
"Currently the EMA and the FDA limit the aluminium content of a vaccine to 1.25 mg [1250 mcg]."
"This limit is based upon the aluminium adjuvant’s efficacy in inducing antibody titres. Perhaps now is the time to revise this limit based upon additional factors of vaccine safety."
Source: An Aluminum Adjuvant in a Vaccine is an Acute Exposure to Aluminum
